Dissertation Title: Activation of Vibrio Cholerae Quorum Sensing to Manipulate Virulence

Department: Molecular Biology

Advisor(s): Bonnie Bassler

Bio: Amanda Hurley grew up on a sheep farm in Rollinsford, NH. She majored in Microbiology at the University of New Hampshire and then worked for the National Institutes of Health to study the effects of chronic HIV infection on the immune system. After seeing a fabulously intelligent woman give talks on how bacteria can communicate with each other via quorum sensing, she couldn't resist the calling of grad school any longer and applied to the Department of Molecular Biology at Princeton in 2011 and joined Bonnie Bassler's group. Amanda currently studies how Vibrio cholerae, the etiology for the disease cholera, naturally communicates so that she can synthetically manipulate its virulence in the lab.